| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM50403048 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_887613 (CHEMBL2217222) |
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| IC50 | 143000±n/a nM |
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| Citation |  Jain, AK; Vaidya, A; Ravichandran, V; Kashaw, SK; Agrawal, RK Recent developments and biological activities of thiazolidinone derivatives: a review. Bioorg Med Chem20:3378-95 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51390.46 |
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| Organism: | RAT |
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| Description: | P08482 |
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| Residue: | 460 |
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| Sequence: | MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM50403048 |
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| n/a |
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| Name | BDBM50403048 |
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| Synonyms: | CHEMBL2216805 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H20N2OS |
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| Mol. Mass. | 288.408 |
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| SMILES | CN1CCC=C(C1)N1C(SCC1=O)c1ccc(C)cc1 |c:4| |
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| Structure | 
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