| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
|---|
| Ligand | BDBM50215377 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_226359 (CHEMBL858013) |
|---|
| Ki | <10000±n/a nM |
|---|
| Citation |  Masaguer, CF; Formoso, E; Raviña, E; Tristán, H; Loza, MI; Rivas, E; Fontenla, JA Butyrophenone analogues in the carbazole series: synthesis and determination of affinities at D2 and 5-HT2A receptors. Bioorg Med Chem Lett8:3571-6 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 2A |
|---|
| Name: | 5-hydroxytryptamine receptor 2A |
|---|
| Synonyms: | 5-HT-2A | 5-HT2 | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_RAT | Htr2 | Htr2a | Serotonin Receptor 2A |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 52852.05 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | Rat cortex membranes 5-HT2A receptors. |
|---|
| Residue: | 471 |
|---|
| Sequence: | MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYK
SSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
|
|
|
|---|
| BDBM50215377 |
|---|
| n/a |
|---|
| Name | BDBM50215377 |
|---|
| Synonyms: | CHEMBL118947 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H22N2O |
|---|
| Mol. Mass. | 270.3694 |
|---|
| SMILES | CCN(CC)CC1Cc2[nH]c3ccccc3c2C(=O)C1 |
|---|
| Structure | 
|
|---|
Search and Browse
