| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 1A1 |
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| Ligand | BDBM50404852 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_36222 (CHEMBL647918) |
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| IC50 | 23988±n/a nM |
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| Citation |  Little, PJ; Ryan, AJ Inhibitors of hepatic mixed-function oxidases. 4. Effects of benzimidazole and related compounds on aryl hydrocarbon hydroxylase activity from phenobarbitone and 3-methylcholanthrene induced rats. J Med Chem25:622-6 (1982) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 1A1 |
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| Name: | Cytochrome P450 1A1 |
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| Synonyms: | CP1A1_RAT | Cyp1a-1 | Cyp1a1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59401.56 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_774160 |
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| Residue: | 524 |
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| Sequence: | MPSVYGFPAFTSATELLLAVTTFCLGFWVVRVTRTWVPKGLKSPPGPWGLPFIGHVLTLG
KNPHLSLTKLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVKQGDDFKGRPDLYSFTLIA
NGQSMTFNPDSGPLWAARRRLAQNALKSFSIASDPTLASSCYLEEHVSKEAEYLISKFQK
LMAEVGHFDPFKYLVVSVANVICAICFGRRYDHDDQELLSIVNLSNEFGEVTGSGYPADF
IPILRYLPNSSLDAFKDLNKKFYSFMKKLIKEHYRTFEKGHIRDITDSLIEHCQDRRLDE
NANVQLSDDKVITIVFDLFGAGFDTITTAISWSLMYLVTNPRIQRKIQEELDTVIGRDRQ
PRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTIRDTSLNGFYIPKGHCVFVNQWQVNH
DQELWGDPNEFRPERFLTSSGTLDKHLSEKVILFGLGKRKCIGETIGRLEVFLFLAILLQ
QMEFNVSPGEKVDMTPAYGLTLKHARCEHFQVQMRSSGPQHLQA
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| BDBM50404852 |
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| n/a |
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| Name | BDBM50404852 |
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| Synonyms: | CHEMBL345675 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H20N2 |
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| Mol. Mass. | 216.322 |
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| SMILES | CCCCCCCc1nc2ccccc2[nH]1 |
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| Structure | 
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