| Reaction Details |
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 | Report a problem with these data |
| Target | 2-Hydroxyacid oxidase 1 |
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| Ligand | BDBM50125793 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_71275 (CHEMBL685164) |
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| IC50 | 3000±n/a nM |
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| Citation |  Williams, HW; Eichler, E; Randall, WC; Rooney, CS; Cragoe, EJ; Streeter, KB; Schwam, H; Michelson, SR; Patchett, AA; Taub, D Inhibitors of glycolic acid oxidase. 4-substituted 2,4-dioxobutanoic acid derivatives. J Med Chem26:1196-200 (1983) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 2-Hydroxyacid oxidase 1 |
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| Name: | 2-Hydroxyacid oxidase 1 |
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| Synonyms: | GOX1 | HAO1 | HAOX1_HUMAN | Hydroxyacid oxidase 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40927.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_71275 |
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| Residue: | 370 |
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| Sequence: | MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAET
DLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAE
AGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQ
LRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILR
GDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDV
LKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV
RKNPLAVSKI
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| BDBM50125793 |
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| n/a |
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| Name | BDBM50125793 |
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| Synonyms: | 4-(4-Cyclohexyl-phenyl)-2-hydroxy-4-oxo-but-2-enoic acid | CHEMBL16405 | CHEMBL417634 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H18O4 |
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| Mol. Mass. | 274.3117 |
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| SMILES | OC(=O)C(=O)CC(=O)c1ccc(cc1)C1CCCCC1 |
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| Structure | 
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