Reaction Details |
| Report a problem with these data |
Target | 5-hydroxytryptamine receptor 1D |
---|
Ligand | BDBM50407361 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_1961 (CHEMBL875911) |
---|
IC50 | 7.94±n/a nM |
---|
Citation | Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Synthesis and serotonergic activity of N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine and analogues: potent agonists for 5-HT1D receptors. J Med Chem38:1799-810 (1995) [PubMed] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
5-hydroxytryptamine receptor 1D |
---|
Name: | 5-hydroxytryptamine receptor 1D |
Synonyms: | 5HT1D_PIG | HTR1D | Serotonin 1d (5-HT1d) receptor |
Type: | PROTEIN |
Mol. Mass.: | 32680.56 |
Organism: | Sus scrofa |
Description: | ChEMBL_1963 |
Residue: | 291 |
Sequence: | AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAI
TDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIY
STCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSL
HEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVA
SLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV
|
|
|
BDBM50407361 |
---|
n/a |
---|
Name | BDBM50407361 |
Synonyms: | CHEMBL53764 |
Type | Small organic molecule |
Emp. Form. | C16H20N4 |
Mol. Mass. | 268.3568 |
SMILES | CN(C)CCc1c[nH]c2ccc(cc12)-n1ccnc1C |
Structure |
|