| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dopamine beta-hydroxylase |
|---|
| Ligand | BDBM50406077 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_59302 (CHEMBL669437) |
|---|
| IC50 | 154881.66±n/a nM |
|---|
| Citation |  Hahn, M; Rogers, D Receptor surface models. 2. Application to quantitative structure-activity relationships studies. J Med Chem38:2091-102 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Dopamine beta-hydroxylase |
|---|
| Name: | Dopamine beta-hydroxylase |
|---|
| Synonyms: | DBH | DOPO_HUMAN | Dopamine beta-monooxygenase | Soluble dopamine beta-hydroxylase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 69062.68 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_59428 |
|---|
| Residue: | 617 |
|---|
| Sequence: | MPALSRWASLPGPSMREAAFMYSTAVAIFLVILVAALQGSAPRESPLPYHIPLDPEGSLE
LSWNVSYTQEAIHFQLLVRRLKAGVLFGMSDRGELENADLVVLWTDGDTAYFADAWSDQK
GQIHLDPQQDYQLLQVQRTPEGLTLLFKRPFGTCDPKDYLIEDGTVHLVYGILEEPFRSL
EAINGSGLQMGLQRVQLLKPNIPEPELPSDACTMEVQAPNIQIPSQETTYWCYIKELPKG
FSRHHIIKYEPIVTKGNEALVHHMEVFQCAPEMDSVPHFSGPCDSKMKPDRLNYCRHVLA
AWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRNDSSGIRLYYTAKLRRF
NAGIMELGLVYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGIHIFASQLHTHLTGRKV
VTVLVRDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLITSCTYNTEDRELATVGG
FGILEEMCVNYVHYYPQTQLELCKSAVDAGFLQKYFHLINRFNNEDVCTCPQASVSQQFT
SVPWNSFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLPKVISTLEEPTPQCPTSQ
GRSPAGPTVVSIGGGKG
|
|
|
|---|
| BDBM50406077 |
|---|
| n/a |
|---|
| Name | BDBM50406077 |
|---|
| Synonyms: | CHEMBL63667 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H10Cl2N2OS |
|---|
| Mol. Mass. | 289.181 |
|---|
| SMILES | COc1cc(Cl)c(Cn2cc[nH]c2=S)c(Cl)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
