| Reaction Details |
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 | Report a problem with these data |
| Target | B2 bradykinin receptor |
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| Ligand | BDBM50408044 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_40445 (CHEMBL652384) |
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| Kd | 173.78±n/a nM |
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| Citation |  Goodfellow, VS; Marathe, MV; Kuhlman, KG; Fitzpatrick, TD; Cuadrado, D; Hanson, W; Zuzack, JS; Ross, SE; Wieczorek, M; Burkard, M; Whalley, ET Bradykinin receptor antagonists containing N-substituted amino acids: in vitro and in vivo B(2) and B(1) receptor antagonist activity. J Med Chem39:1472-84 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| B2 bradykinin receptor |
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| Name: | B2 bradykinin receptor |
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| Synonyms: | B2 BRADYKININ | B2 bradykinin receptor | B2R | BK-2 receptor | BKRB2_RAT | Bdkrb2 | Bradykinin B2 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44941.22 |
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| Organism: | RAT |
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| Description: | B2 BRADYKININ BDKRB2 RAT::P25023 |
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| Residue: | 396 |
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| Sequence: | MDTRSSLCPKTQAVVAVFWGPGCHLSTCIEMFNITTQALGSAHNGTFSEVNCPDTEWWSW
LNAIQAPFLWVLFLLAALENIFVLSVFCLHKTNCTVAEIYLGNLAAADLILACGLPFWAI
TIANNFDWLFGEVLCRVVNTMIYMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAK
LYSLVIWSCTLLLSSPMLVFRTMKDYREEGHNVTACVIVYPSRSWEVFTNMLLNLVGFLL
PLSIITFCTVRIMQVLRNNEMKKFKEVQTEKKATVLVLAVLGLFVLCWFPFQISTFLDTL
LRLGVLSGCWNERAVDIVTQISSYVAYSNSCLNPLVYVIVGKRFRKKSREVYQAICRKGG
CMGESVQMENSMGTLRTSISVDRQIHKLQDWAGNKQ
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| BDBM50408044 |
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| n/a |
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| Name | BDBM50408044 |
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| Synonyms: | CHEMBL3038104 |
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| Type | Small organic molecule |
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| Emp. Form. | C52H79N15O12S |
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| Mol. Mass. | 1138.342 |
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| SMILES | [#7]-[#6](-[#7])-[#7]-[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-1-[#6]-[#6@H](-[#8])-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1cccs1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-1-[#6]-c2ccccc2-[#6]-[#6@@H]-1-[#6](=O)-[#7](-[#6]-[#6](-[#8])=O)-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 |
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| Structure | 
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