Reaction Details |
| Report a problem with these data |
Target | Beta-3 adrenergic receptor |
---|
Ligand | BDBM50409476 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_218265 (CHEMBL819430) |
---|
EC50 | 831.76±n/a nM |
---|
Citation | Tanaka, N; Tamai, T; Mukaiyama, H; Hirabayashi, A; Muranaka, H; Akahane, S; Miyata, H; Akahane, M Discovery of novel N-phenylglycine derivatives as potent and selective beta(3)-adrenoceptor agonists for the treatment of frequent urination and urinary incontinence. J Med Chem44:1436-45 (2001) [PubMed] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Beta-3 adrenergic receptor |
---|
Name: | Beta-3 adrenergic receptor |
Synonyms: | ADRB3_RAT | Adrb3 | Adrb3r | Adrenergic receptor beta | Beta-3 adrenergic receptor |
Type: | PROTEIN |
Mol. Mass.: | 43161.83 |
Organism: | Rattus norvegicus |
Description: | ChEMBL_1509452 |
Residue: | 400 |
Sequence: | MAPWPHKNGSLAFWSDAPTLDPSAANTSGLPGVPWAAALAGALLALATVGGNLLVITAIA
RTPRLQTITNVFVTSLATADLVVGLLVMPPGATLALTGHWPLGATGCELWTSVDVLCVTA
SIETLCALAVDRYLAVTNPLRYGTLVTKRRARAAVVLVWIVSATVSFAPIMSQWWRVGAD
AEAQECHSNPRCCSFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVAKRQRRLLRRELG
RFPPEESPRSPSRSPSPATVGTPTASDGVPSCGRRPARLLPLGEHRALRTLGLIMGIFSL
CWLPFFLANVLRALVGPSLVPSGVFIALNWLGYANSAFNPLIYCRSPDFRDAFRRLLCSY
GGRGPEEPRVVTFPASPVASRQNSPLNRFDGYEGERPFPT
|
|
|
BDBM50409476 |
---|
n/a |
---|
Name | BDBM50409476 |
Synonyms: | CHEMBL289670 |
Type | Small organic molecule |
Emp. Form. | C21H26N2O6 |
Mol. Mass. | 402.4409 |
SMILES | C[C@H](NCCc1ccc(cc1)N(CC(O)=O)CC(O)=O)[C@H](O)c1ccc(O)cc1 |
Structure |
|