| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1B adrenergic receptor |
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| Ligand | BDBM50411195 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_412941 (CHEMBL910640) |
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| Ki | 11±n/a nM |
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| Citation |  Pallavicini, M; Budriesi, R; Fumagalli, L; Ioan, P; Chiarini, A; Bolchi, C; Ugenti, MP; Colleoni, S; Gobbi, M; Valoti, E WB4101-related compounds: new, subtype-selective alpha1-adrenoreceptor antagonists (or inverse agonists?). J Med Chem49:7140-9 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1B adrenergic receptor |
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| Name: | Alpha-1B adrenergic receptor |
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| Synonyms: | ADA1B_HUMAN | ADRA1B | Adrenergic alpha1B | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1B-adrenoceptor | Alpha 1B-adrenoreceptor | Alpha-1B adrenergic receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 56862.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35368 |
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| Residue: | 520 |
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| Sequence: | MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGP
LLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFV
RILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRT
LPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLT
EPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
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| BDBM50411195 |
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| n/a |
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| Name | BDBM50411195 |
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| Synonyms: | CHEMBL214694 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H25NO4 |
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| Mol. Mass. | 391.4596 |
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| SMILES | COc1ccc(cc1OCCNC[C@H]1COc2ccccc2O1)-c1ccccc1 |r| |
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| Structure | 
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