| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histidine-rich protein PFHRP-II |
|---|
| Ligand | BDBM50202591 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_423821 (CHEMBL910656) |
|---|
| IC50 | 560±n/a nM |
|---|
| Citation |  Solomon, VR; Haq, W; Srivastava, K; Puri, SK; Katti, SB Synthesis and antimalarial activity of side chain modified 4-aminoquinoline derivatives. J Med Chem50:394-8 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histidine-rich protein PFHRP-II |
|---|
| Name: | Histidine-rich protein PFHRP-II |
|---|
| Synonyms: | HRP1_PLAFA | Histidine-rich protein | Histidine-rich protein PFHRP-II |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 35156.49 |
|---|
| Organism: | Plasmodium falciparum |
|---|
| Description: | ChEMBL_500704 |
|---|
| Residue: | 332 |
|---|
| Sequence: | MVSFSKNKVLSAAVFASVLLLDNNNSAFNNNLCSKNAKGLNLNKRLLHETQAHVDDAHHA
HHVADAHHAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHA
ADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAAYAHHAHHASDAHHAADAHHAAYA
HHAHHAADAHHAADAHHAAYAHHAHHAADAHHAADAHHATDAHHAHHAADAHHATDAHHA
ADAHHAADAHHATDAHHAADAHHATDAHHAADAHHAADAHHATDSHHAHHAADAHHAAAH
HATDAHHAAAHHATDAHHAAAHHEAATHCLRH
|
|
|
|---|
| BDBM50202591 |
|---|
| n/a |
|---|
| Name | BDBM50202591 |
|---|
| Synonyms: | 2-(4-chloro-phenyl)-3-[3-(7-chloroquinolin-4-ylamino)-propyl]-thiazolidin-4-one | CHEMBL376916 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H19Cl2N3OS |
|---|
| Mol. Mass. | 432.366 |
|---|
| SMILES | Clc1ccc(cc1)C1SCC(=O)N1CCCNc1ccnc2cc(Cl)ccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
