| Reaction Details |
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 | Report a problem with these data |
| Target | Calcium-activated potassium channel subunit alpha-1 |
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| Ligand | BDBM50412107 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_532343 (CHEMBL973266) |
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| IC50 | 27542.29±n/a nM |
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| Citation |  Calderone, V; Fiamingo, FL; Amato, G; Giorgi, I; Livi, O; Martelli, A; Martinotti, E New amido derivatives as potential BKCa potassium channel activators. XI. Eur J Med Chem43:792-9 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcium-activated potassium channel subunit alpha-1 |
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| Name: | Calcium-activated potassium channel subunit alpha-1 |
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| Synonyms: | KCMA1_RAT | Kcnma | Kcnma1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 134382.76 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_510400 |
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| Residue: | 1209 |
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| Sequence: | MANGGGGGGGGSSGSSGGGGGGGGGETALRMSSNIHANHLSLDASSSSSSSSSSSSSSSS
SVHEPKMDALIIPVTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCC
HCGGKTKEAQKINNGSSQADGTLKPVDEKEEVVAAEVGWMTSVKDWAGVMISAQTLTGRV
LVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDK
LWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIK
LVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLE
SVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARV
KIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSN
EMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRSRKRILINPGNHLKIQ
EGTLGFFIASDAKEVKRAFFYCKACHDDVTDPKRIKKCGCRRLEDEQPPTLSPKKKQRNG
GMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEA
AMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETL
HNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSM
QFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELAKPGKLPL
VSVNQEKNSGTHILMITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSL
MSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALL
DGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFEL
VPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRPNRPKSRESRD
KQKKEMVYR
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| BDBM50412107 |
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| n/a |
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| Name | BDBM50412107 |
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| Synonyms: | CHEMBL452008 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H11F4NO |
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| Mol. Mass. | 297.2476 |
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| SMILES | Fc1ccccc1NC(=O)Cc1ccccc1C(F)(F)F |
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| Structure | 
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