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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Adenosine receptor A1 | ||
| Ligand | BDBM50412196 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_530419 (CHEMBL972184) | ||
| Ki | 1850120.43±n/a nM | ||
| Citation |  Massarelli, I; Coi, A; Pietra, D; Nofal, FA; Biagi, G; Giorgi, I; Leonardi, M; Fiamingo, F; Bianucci, AM QSAR study on a novel series of 8-azaadenine analogues proposed as A1 adenosine receptor antagonists. Eur J Med Chem43:114-21 (2008) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Adenosine receptor A1 | |||
| Name: | Adenosine receptor A1 | ||
| Synonyms: | AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 36602.99 | ||
| Organism: | BOVINE | ||
| Description: | ADENOSINE 0 BOVINE::P28190 | ||
| Residue: | 326 | ||
| Sequence: |
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| BDBM50412196 | |||
| n/a | |||
| Name | BDBM50412196 | ||
| Synonyms: | CHEMBL452257 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H23FN6O | ||
| Mol. Mass. | 418.4667 | ||
| SMILES | OC1CCC(CC1)Nc1nc(nc2n(Cc3ccccc3F)nnc12)-c1ccccc1 |(.4,-38.89,;-.93,-39.67,;-.94,-41.21,;-2.26,-41.98,;-3.6,-41.22,;-3.61,-39.67,;-2.27,-38.9,;-4.93,-41.99,;-4.92,-43.53,;-6.25,-44.3,;-6.25,-45.85,;-4.92,-46.62,;-3.58,-45.85,;-2.11,-46.32,;-1.63,-47.79,;-2.66,-48.93,;-4.16,-48.61,;-5.19,-49.75,;-4.71,-51.22,;-3.2,-51.53,;-2.18,-50.39,;-.67,-50.7,;-1.19,-45.07,;-2.11,-43.81,;-3.58,-44.29,;-7.58,-46.61,;-8.91,-45.84,;-10.25,-46.6,;-10.25,-48.14,;-8.91,-48.92,;-7.58,-48.14,)| | ||
| Structure | 
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