| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50196015 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_530419 (CHEMBL972184) |
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| Ki | 6499800.1±n/a nM |
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| Citation |  Massarelli, I; Coi, A; Pietra, D; Nofal, FA; Biagi, G; Giorgi, I; Leonardi, M; Fiamingo, F; Bianucci, AM QSAR study on a novel series of 8-azaadenine analogues proposed as A1 adenosine receptor antagonists. Eur J Med Chem43:114-21 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36602.99 |
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| Organism: | BOVINE |
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| Description: | ADENOSINE 0 BOVINE::P28190 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
PRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPVDEDAPAERPDD
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| BDBM50196015 |
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| n/a |
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| Name | BDBM50196015 |
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| Synonyms: | 3-(2-(trifluoromethyl)benzyl)-N-butyl-5-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine | CHEMBL228225 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21F3N6 |
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| Mol. Mass. | 426.4375 |
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| SMILES | CCCCNc1nc(nc2n(Cc3ccccc3C(F)(F)F)nnc12)-c1ccccc1 |
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| Structure | 
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