| Reaction Details |
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 | Report a problem with these data |
| Target | Calcium-activated potassium channel subunit alpha-1 |
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| Ligand | BDBM67581 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_558735 (CHEMBL954137) |
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| IC50 | 3090.3±n/a nM |
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| Citation |  Coi, A; Fiamingo, FL; Livi, O; Calderone, V; Martelli, A; Massarelli, I; Bianucci, AM QSAR studies on BK channel activators. Bioorg Med Chem17:319-25 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcium-activated potassium channel subunit alpha-1 |
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| Name: | Calcium-activated potassium channel subunit alpha-1 |
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| Synonyms: | Calcium-activated potassium channel alpha/beta 1 | KCMA1_HUMAN | KCNMA | KCNMA1 | Large conductance calcium-activated potassium channel subfamily M alpha member 1 isoform b | SLO |
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| Type: | PROTEIN |
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| Mol. Mass.: | 137567.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_938830 |
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| Residue: | 1236 |
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| Sequence: | MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSS
VHEPKMDALIIPVTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCH
CGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKL
WFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKL
VNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYA
KTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLES
VSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVK
IESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSW
NWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNE
MYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLG
FFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERD
CSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQRNGGMRNSPN
TSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSG
HVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVS
ILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIG
VLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDD
DPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEEN
ALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRL
RDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSS
KKSSSVHSIPSTANRQNRPKSRESRDKQKYVQEERL
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| BDBM67581 |
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| n/a |
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| Name | BDBM67581 |
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| Synonyms: | MLS000050452 | N-(5-chloranyl-2-oxidanyl-phenyl)-2-ethoxy-benzamide | N-(5-chloro-2-hydroxy-phenyl)-2-ethoxy-benzamide | N-(5-chloro-2-hydroxyphenyl)-2-ethoxybenzamide | SMR000076353 | cid_2953683 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14ClNO3 |
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| Mol. Mass. | 291.73 |
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| SMILES | CCOc1ccccc1C(=O)Nc1cc(Cl)ccc1O |
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| Structure | 
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