| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
|---|
| Ligand | BDBM50412874 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_515302 (CHEMBL1035637) |
|---|
| IC50 | 100000±n/a nM |
|---|
| Citation |  Chimenti, F; Fioravanti, R; Bolasco, A; Manna, F; Chimenti, P; Secci, D; Rossi, F; Turini, P; Ortuso, F; Alcaro, S; Cardia, MC Synthesis, molecular modeling studies and selective inhibitory activity against MAO of N1-propanoyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives. Eur J Med Chem43:2262-7 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] B |
|---|
| Name: | Amine oxidase [flavin-containing] B |
|---|
| Synonyms: | AOFB_BOVIN | Amine oxidase [flavin-containing] B | MAO-B | MAOB | Monoamine Oxidase Type B (MAO-B) | Monoamine oxidase | Monoamine oxidase B | Monoamine oxidase type B |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 58428.94 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_1501478 |
|---|
| Residue: | 520 |
|---|
| Sequence: | MSSKCDVVVVGGGISGMAAAKLLHDSGLNVIVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNHILRLSKELGLETYKVNEVERLIHHTKGKSYPFRGSFPSVWNPITYLDHNNLWR
TMDDMGREIPSDAPWKAPLAEQWDLMTMKELLDKICWTESSKQLAILFVNLCVTAEIHEV
SALWFLWYVKQCGGTTRIFSTSNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIHIDQ
TGENVLVETLNHELYEAKYVISAVPPVLGMKIHFNPPLPMMRNQLITRVPLGSVIKSIVY
YKEPFWRNMDYCGSMIIEGEEAPVAYALDDTKPDGSYPAIIGFILAHKARKLARLTKEER
LKKLCDLYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTSYFPPGIMTQYGRVLRQPVGR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWLPEPESVDVPAKPITTT
FLQRHLPSVPGLLKLIGLTTIFSATALGFLAHKRGLLVRI
|
|
|
|---|
| BDBM50412874 |
|---|
| n/a |
|---|
| Name | BDBM50412874 |
|---|
| Synonyms: | CHEMBL472713 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H20N2O2 |
|---|
| Mol. Mass. | 308.3743 |
|---|
| SMILES | CCC(=O)N1N=C(CC1c1ccc(OC)cc1)c1ccccc1 |c:5| |
|---|
| Structure | 
|
|---|
Search and Browse
