| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mas-related G-protein coupled receptor member X1 |
|---|
| Ligand | BDBM50412983 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_516621 (CHEMBL991397) |
|---|
| EC50 | 8318±n/a nM |
|---|
| Citation |  Wroblowski, B; Wigglesworth, MJ; Szekeres, PG; Smith, GD; Rahman, SS; Nicholson, NH; Muir, AI; Hall, A; Heer, JP; Garland, SL; Coates, WJ The discovery of a selective, small molecule agonist for the MAS-related gene X1 receptor. J Med Chem52:818-25 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mas-related G-protein coupled receptor member X1 |
|---|
| Name: | Mas-related G-protein coupled receptor member X1 |
|---|
| Synonyms: | MRGPRX1 | MRGX1 | MRGX1_HUMAN | SNSR3 | SNSR4 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 36253.68 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_516621 |
|---|
| Residue: | 322 |
|---|
| Sequence: | MDPTISTLDTELTPINGTEETLCYKQTLSLTVLTCIVSLVGLTGNAVVLWLLGCRMRRNA
FSIYILNLAAADFLFLSGRLIYSLLSFISIPHTISKILYPVMMFSYFAGLSFLSAVSTER
CLSVLWPIWYRCHRPTHLSAVVCVLLWALSLLRSILEWMLCGFLFSGADSAWCQTSDFIT
VAWLIFLCVVLCGSSLVLLIRILCGSRKIPLTRLYVTILLTVLVFLLCGLPFGIQFFLFL
WIHVDREVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDASE
VDEGGGQLPEEILELSGSRLEQ
|
|
|
|---|
| BDBM50412983 |
|---|
| n/a |
|---|
| Name | BDBM50412983 |
|---|
| Synonyms: | CHEMBL458001 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H26ClN5O2 |
|---|
| Mol. Mass. | 499.991 |
|---|
| SMILES | Clc1c(cnn(Cc2cccc(NC(=O)c3ccc(cc3)-c3ccccc3)c2)c1=O)N1CCNCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
