| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide S receptor |
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| Ligand | BDBM50412707 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_523542 (CHEMBL1001556) |
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| EC50 | 4.8±n/a nM |
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| Citation |  Guerrini, R; Camarda, V; Trapella, C; Caló, G; Rizzi, A; Ruzza, C; Fiorini, S; Marzola, E; Reinscheid, RK; Regoli, D; Salvadori, S Further studies at neuropeptide s position 5: discovery of novel neuropeptide S receptor antagonists. J Med Chem52:4068-71 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide S receptor |
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| Name: | Neuropeptide S receptor |
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| Synonyms: | Gpr154 | NPSR1_MOUSE | Npsr1 | Pgr14 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42447.53 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_445691 |
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| Residue: | 371 |
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| Sequence: | MPANLTEGSFHANQTVPMLDSSPVACTEIVTFTEALVAEEWGSFYSSFKTEQLITLWVLF
VVTIVGNSVVLFSTCRRKRKSRMTFFVTQLAITDSFTGLINILTDIIWRFTGDFMAPDLV
CRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQAKVLIGIAWSLSFLFSIP
TLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLAIISVIYGLVIRTIWMK
SKTHETVISNCSDGKLCCSYNRGLISKAKIKAIKYSIVIILAFICCWSPYFLFDILDNFN
VLPDTKERFYASVIIQNLPALNSAINPLIYCIFSSSICSPCKMQRSQDSRMTYRERSERH
EMQILSKPEFI
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| BDBM50412707 |
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| n/a |
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| Name | BDBM50412707 |
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| Synonyms: | CHEMBL230333 |
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| Type | Small organic molecule |
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| Emp. Form. | C93H155N31O28S |
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| Mol. Mass. | 2187.482 |
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| SMILES | CSCC[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CO)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(O)=O |r| |
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| Structure | 
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