| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide S receptor |
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| Ligand | BDBM50413778 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_523542 (CHEMBL1001556) |
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| EC50 | 1660±n/a nM |
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| Citation |  Guerrini, R; Camarda, V; Trapella, C; Caló, G; Rizzi, A; Ruzza, C; Fiorini, S; Marzola, E; Reinscheid, RK; Regoli, D; Salvadori, S Further studies at neuropeptide s position 5: discovery of novel neuropeptide S receptor antagonists. J Med Chem52:4068-71 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide S receptor |
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| Name: | Neuropeptide S receptor |
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| Synonyms: | Gpr154 | NPSR1_MOUSE | Npsr1 | Pgr14 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42447.53 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_445691 |
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| Residue: | 371 |
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| Sequence: | MPANLTEGSFHANQTVPMLDSSPVACTEIVTFTEALVAEEWGSFYSSFKTEQLITLWVLF
VVTIVGNSVVLFSTCRRKRKSRMTFFVTQLAITDSFTGLINILTDIIWRFTGDFMAPDLV
CRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQAKVLIGIAWSLSFLFSIP
TLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLAIISVIYGLVIRTIWMK
SKTHETVISNCSDGKLCCSYNRGLISKAKIKAIKYSIVIILAFICCWSPYFLFDILDNFN
VLPDTKERFYASVIIQNLPALNSAINPLIYCIFSSSICSPCKMQRSQDSRMTYRERSERH
EMQILSKPEFI
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| BDBM50413778 |
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| n/a |
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| Name | BDBM50413778 |
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| Synonyms: | CHEMBL500443 |
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| Type | Small organic molecule |
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| Emp. Form. | C95H160N30O26S |
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| Mol. Mass. | 2170.537 |
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| SMILES | [#6]-[#16]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#6]C([#6])([#6])[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#8])-[#6](-[#6])-[#6])-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](-[#8])=O |r| |
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| Structure | 
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