| Reaction Details |
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 | Report a problem with these data |
| Target | Ecdysone receptor |
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| Ligand | BDBM50414651 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_582869 (CHEMBL1051107) |
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| IC50 | 2570.4±n/a nM |
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| Citation |  Harada, T; Nakagawa, Y; Akamatsu, M; Miyagawa, H Evaluation of hydrogen bonds of ecdysteroids in the ligand-receptor interactions using a protein modeling system. Bioorg Med Chem17:5868-73 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ecdysone receptor |
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| Name: | Ecdysone receptor |
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| Synonyms: | 20-hydroxy-ecdysone receptor | 20E receptor | ECR_DROME | EcR | EcRH | Ecdysteroid receptor | NR1H1 | Nuclear receptor subfamily 1 group H member 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 93857.12 |
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| Organism: | Drosophila melanogaster |
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| Description: | ChEMBL_582869 |
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| Residue: | 878 |
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| Sequence: | MKRRWSNNGGFMRLPEESSSEVTSSSNGLVLPSGVNMSPSSLDSHDYCDQDLWLCGNESG
SFGGSNGHGLSQQQQSVITLAMHGCSSTLPAQTTIIPINGNANGNGGSTNGQYVPGATNL
GALANGMLNGGFNGMQQQIQNGHGLINSTTPSTPTTPLHLQQNLGGAGGGGIGGMGILHH
ANGTPNGLIGVVGGGGGVGLGVGGGGVGGLGMQHTPRSDSVNSISSGRDDLSPSSSLNGY
SANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCC
KFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSP
SSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQ
LAVIYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKG
LPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMAGMADN
IEDLLHFCRQMFSMKVDNVEYALLTAIVIFSDRPGLEKAQLVEAIQSYYIDTLRIYILNR
HCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQ
SHLQITQEENERLERAERMRASVGGAITAGIDCDSASTSAAAAAAQHQPQPQPQPQPSSL
TQNDSQHQTQPQLQPQLPPQLQGQLQPQLQPQLQTQLQPQIQPQPQLLPVSAPVPASVTA
PGSLSAVSTSSEYMGGSAAIGPITPATTSSITAAVTASSTTSAVPMGNGVGVGVGVGGNV
SMYANAQTAMALMGVALHSHQEQLIGGVAVKSEHSTTA
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| BDBM50414651 |
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| n/a |
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| Name | BDBM50414651 |
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| Synonyms: | ECDYSONE |
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| Type | Small organic molecule |
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| Emp. Form. | C27H44O6 |
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| Mol. Mass. | 464.6347 |
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| SMILES | C[C@H]([C@@H](O)CCC(C)(C)O)[C@@H]1CC[C@]2(O)C3=CC(=O)[C@@H]4C[C@H](O)[C@@H](O)C[C@@]4(C)[C@@H]3CC[C@@]12C |r,t:15,@@:6| |
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| Structure | 
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