| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50415447 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_611641 (CHEMBL1071011) |
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| Ki | 93.33±n/a nM |
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| Citation |  Rodríguez-Borges, JE; García-Mera, X; Balo, MC; Brea, J; Caamaño, O; Fernández, F; López, C; Loza, MI; Nieto, MI Synthesis and pharmacological evaluation of novel 1,3,8- and 1,3,7,8-substituted xanthines as adenosine receptor antagonists. Bioorg Med Chem18:2001-9 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50415447 |
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| n/a |
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| Name | BDBM50415447 |
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| Synonyms: | CHEMBL597973 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H22N4O4S |
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| Mol. Mass. | 390.457 |
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| SMILES | CCCn1c(=O)n(CCS(=O)(=O)CC)c2nc([nH]c2c1=O)-c1ccccc1 |
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| Structure | 
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