| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM50079043 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_632192 (CHEMBL1106525) |
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| Ki | 35700000±n/a nM |
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| Citation |  Sethi, KK; Verma, SM; Prasanthi, N; Sahoo, SK; Parhi, RN; Suresh, P 3D-QSAR study of benzene sulfonamide analogs as carbonic anhydrase II inhibitors. Bioorg Med Chem Lett20:3089-93 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29250.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00918 |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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| BDBM50079043 |
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| n/a |
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| Name | BDBM50079043 |
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| Synonyms: | 4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid diamide | 4-amino-5,6-dichlorobenzene-1,3-disulfonamide | BDBM50222601 | CHEMBL269628 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H7Cl2N3O4S2 |
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| Mol. Mass. | 320.173 |
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| SMILES | Nc1c(Cl)c(Cl)c(cc1S(N)(=O)=O)S(N)(=O)=O |
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| Structure | 
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