| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-1B adrenergic receptor |
|---|
| Ligand | BDBM50417541 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_693738 (CHEMBL1638257) |
|---|
| Ki | 1.91±n/a nM |
|---|
| Citation |  Sagratini, G; Angeli, P; Buccioni, M; Gulini, U; Marucci, G; Melchiorre, C; Poggesi, E; Giardinà, D Synthesis anda1-adrenoceptor antagonist activity of tamsulosin analogues. Eur J Med Chem45:5800-7 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-1B adrenergic receptor |
|---|
| Name: | Alpha-1B adrenergic receptor |
|---|
| Synonyms: | ADA1B_HUMAN | ADRA1B | Adrenergic alpha1B | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1B-adrenoceptor | Alpha 1B-adrenoreceptor | Alpha-1B adrenergic receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 56862.13 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35368 |
|---|
| Residue: | 520 |
|---|
| Sequence: | MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGP
LLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFV
RILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRT
LPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLT
EPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
|
|
|
|---|
| BDBM50417541 |
|---|
| n/a |
|---|
| Name | BDBM50417541 |
|---|
| Synonyms: | CHEMBL1630938 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H30N2O5S |
|---|
| Mol. Mass. | 422.538 |
|---|
| SMILES | COc1ccc(C[C@@H](C)NCCOc2ccccc2OC(C)C)cc1S(N)(=O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
