| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 3A6 |
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| Ligand | BDBM50014323 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_738411 (CHEMBL1743488) |
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| Ki | 80100±n/a nM |
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| Citation |  Fontana, E; Dansette, PM; Poli, SM Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Curr Drug Metab6:413-54 (2005) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Cytochrome P450 3A6 |
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| Name: | Cytochrome P450 3A6 |
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| Synonyms: | CP3A6_RABIT | CYP3A6 | CYPIIIA6 | Cytochrome P450-3C |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57463.93 |
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| Organism: | Oryctolagus cuniculus |
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| Description: | ChEMBL_738411 |
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| Residue: | 501 |
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| Sequence: | MDLIFSLETWVLLAASLVLLYLYGTSTHGLFKKMGIPGPTPLPFIGTILEYRKGIWDFDI
ECRKKYGKMWGLFDGRQPLMVITDPDMIKTVLVKECYSVFTNRRSFGPVGFMKKAVSISE
DEDWKRVRTLLSPTFTSGKLKEMLPIIAQYGDVLVKNLRQEAEKGKPVDLKEIFGAYSMD
VITGTSFGVNIDSLRNPQDPFVKNVRRLLKFSFFDPLLLSITLFPFLTPIFEALHISMFP
KDVMDFLKTSVEKIKDDRLKDKQKRRVDFLQLMINSQNSKEIDSHKALDDIEVVAQSIII
LFAGYETTSSTLSFIMHLLATHPDVQQKLQEEIDTLLPNKELATYDTLVKMEYLDMVVNE
TLRLYPIAGRLERVCKKDVDINGTFIPKGTIVMMPTYALHRDPQHWTEPDEFRPERFSKK
NKDNINPYIYHPFGAGPRNCLGMRFALMNIKLALVRLMQNFSFKLCKETQVPLKLGKQGL
LQPEKPIVLKVVSRDGIIRGA
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|
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| BDBM50014323 |
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| n/a |
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| Name | BDBM50014323 |
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| Synonyms: | 2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE | 2-Phenyl-benzo[h]chromen-4-one | 7,8-Benzoflavone | CHEMBL283196 | alpha-naphthoflavone |
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| Type | Small organic molecule |
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| Emp. Form. | C19H12O2 |
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| Mol. Mass. | 272.2974 |
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| SMILES | O=c1cc(oc2c3ccccc3ccc12)-c1ccccc1 |
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| Structure | 
|
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