| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1B |
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| Ligand | BDBM50419034 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_762353 (CHEMBL1816424) |
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| Ki | 181.97±n/a nM |
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| Citation |  Spadoni, G; Bedini, A; Orlando, P; Lucarini, S; Tarzia, G; Mor, M; Rivara, S; Lucini, V; Pannacci, M; Scaglione, F Bivalent ligand approach on N-{2-[(3-methoxyphenyl)methylamino]ethyl}acetamide: synthesis, binding affinity and intrinsic activity for MT(1) and MT(2) melatonin receptors. Bioorg Med Chem19:4910-6 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1B |
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| Name: | Melatonin receptor type 1B |
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| Synonyms: | MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 40203.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49286 |
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| Residue: | 362 |
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| Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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| BDBM50419034 |
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| n/a |
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| Name | BDBM50419034 |
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| Synonyms: | CHEMBL1813321 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H42N4O4 |
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| Mol. Mass. | 498.6575 |
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| SMILES | CN(CCNC(C)=O)c1cccc(OCCCCCCOc2cccc(c2)N(C)CCNC(C)=O)c1 |
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| Structure | 
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