| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
|---|
| Ligand | BDBM50419312 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_773263 (CHEMBL1840215) |
|---|
| EC50 | 0.158489±n/a nM |
|---|
| Citation |  Procopiou, PA; Barrett, VJ; Ford, AJ; Looker, BE; Lunniss, GE; Needham, D; Smith, CE; Somers, G The discovery of long-acting saligeninß2 adrenergic receptor agonists incorporating a urea group. Bioorg Med Chem19:6026-32 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-2 adrenergic receptor |
|---|
| Name: | Beta-2 adrenergic receptor |
|---|
| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 46461.69 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P07550 |
|---|
| Residue: | 413 |
|---|
| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
|
|
|
|---|
| BDBM50419312 |
|---|
| n/a |
|---|
| Name | BDBM50419312 |
|---|
| Synonyms: | CHEMBL1835862 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H41N3O5 |
|---|
| Mol. Mass. | 487.6315 |
|---|
| SMILES | Cc1cc(CCCCOCCCCCCNC[C@H](O)c2ccc(O)c(CO)c2)cc(NC(N)=O)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
