| Reaction Details |
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 | Report a problem with these data |
| Target | fMet-Leu-Phe receptor |
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| Ligand | BDBM50419566 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_796441 (CHEMBL1937756) |
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| IC50 | 316±n/a nM |
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| Citation |  Morley, AD; King, S; Roberts, B; Lever, S; Teobald, B; Fisher, A; Cook, T; Parker, B; Wenlock, M; Phillips, C; Grime, K Lead optimisation of pyrazoles as novel FPR1 antagonists. Bioorg Med Chem Lett22:532-6 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| fMet-Leu-Phe receptor |
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| Name: | fMet-Leu-Phe receptor |
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| Synonyms: | FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38456.14 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_4503779 |
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| Residue: | 350 |
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| Sequence: | METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVT
TISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNF
SPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPL
RVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPML
YVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
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| BDBM50419566 |
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| n/a |
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| Name | BDBM50419566 |
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| Synonyms: | CHEMBL1934417 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H36N4O4S |
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| Mol. Mass. | 464.621 |
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| SMILES | COCCC(C)n1nc(C)c(C(=O)N[C@@H](C)C(C)(C)C)c1NS(=O)(=O)c1ccc(C)cc1 |r| |
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| Structure | 
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