| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50419642 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_797650 (CHEMBL1943768) |
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| EC50 | 2±n/a nM |
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| Citation |  Jacobsen, JR; Choi, SK; Combs, J; Fournier, EJ; Klein, U; Pfeiffer, JW; Thomas, GR; Yu, C; Moran, EJ A multivalent approach to the discovery of long-actingß(2)-adrenoceptor agonists for the treatment of asthma and COPD. Bioorg Med Chem Lett22:1213-8 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50419642 |
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| n/a |
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| Name | BDBM50419642 |
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| Synonyms: | CHEMBL1940821 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29FN2O4 |
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| Mol. Mass. | 440.5072 |
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| SMILES | OCc1cc(ccc1O)C(O)CNCCc1ccc(NCC(O)c2ccc(F)cc2)cc1 |
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| Structure | 
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