| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier organic anion transporter family member 1A1 |
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| Ligand | BDBM50410855 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_839191 (CHEMBL2077862) |
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| Ki | 9270±n/a nM |
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| Citation |  Shitara, Y; Sugiyama, D; Kusuhara, H; Kato, Y; Abe, T; Meier, PJ; Itoh, T; Sugiyama, Y Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport. Pharm Res19:147-53 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier organic anion transporter family member 1A1 |
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| Name: | Solute carrier organic anion transporter family member 1A1 |
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| Synonyms: | OATP-1 | Oatp1 | Oatp1a1 | Organic anion-transporting polypeptide 1 | SO1A1_RAT | Slc21a1 | Slco1a1 | Sodium-independent organic anion transporter 1 | Solute carrier family 21 member 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 74188.94 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_838286 |
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| Residue: | 670 |
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| Sequence: | MEETEKKIATQEGRLFSKMKVFLLSLTCACLTKSLSGVYMNSMLTQIERQFDISTSVAGL
INGSFEIGNLFFIVFVSYFGTKLHRPVVIGIGCVIMGLGCLLMSLPHFFMGRYEYETTIS
PTGNLSSNSFLCMENRTQTLKPTQDPAECVKEMKSLMWICVMVGNIIRGIGETPIVPLGI
SYIEDFAKSENSPLYIGILEMGKVAGPIFGLLLGSYCAQIYVDIGSVNTDDLTITPSDTR
WVGAWWIGFLVCAGVNILTSIPFFFLPKALPKKGQQENVAVTKDGKVEKYGGQAREENLG
ITKDFLTFMKRLFCNPIYMLFILTSVLQVNGFINKFTFLPKYLEQQYGKSTAEAIFLIGV
YSLPPICLGYLIGGFIMKKFKITVKKAAYLAFCLSVFEYLLFLCHFMLTCDNAAVAGLTT
SYKGVQHQLHVESKVLADCNTRCSCSTNTWDPVCGDNGVAYMSACLAGCKKFVGTGTNMV
FQDCSCIQSLGNSSAVLGLCKKGPECANRLQYFLILTIIISFIYSLTAIPGYMVFLRCVK
SEEKSLGVGLHTFCIRVFAGIPAPVYFGALIDRTCLHWGTLKCGQRGACRMYDINSFRHI
YLGLPIALRGSSYLPAFFILILMRKFQFPGDIDSSATDHTEMMLGEKESEHTDVHGSPQV
ENDGELKTKL
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| BDBM50410855 |
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| n/a |
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| Name | BDBM50410855 |
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| Synonyms: | CIN-QUIN | QUINIDEX | QUINIDINE SULFATE |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N2O2 |
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| Mol. Mass. | 324.4168 |
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| SMILES | COc1ccc2nccc([C@H](O)[C@H]3CC4CCN3C[C@@H]4C=C)c2c1 |r,TLB:20:19:12.13:16.15| |
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| Structure | 
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