| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier organic anion transporter family member 1A4 |
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| Ligand | BDBM50370232 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_838985 (CHEMBL2078502) |
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| Ki | 1460±n/a nM |
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| Citation |  Shitara, Y; Sugiyama, D; Kusuhara, H; Kato, Y; Abe, T; Meier, PJ; Itoh, T; Sugiyama, Y Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport. Pharm Res19:147-53 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier organic anion transporter family member 1A4 |
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| Name: | Solute carrier organic anion transporter family member 1A4 |
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| Synonyms: | Brain digoxin carrier protein | Brain-specific organic anion transporter | OATP-B1 | Oatp1a4 | Oatp2 | SO1A4_RAT | Slc21a5 | Slco1a4 | Sodium-independent organic anion-transporting polypeptide 2 | Solute carrier family 21 member 5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 73261.82 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_836631 |
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| Residue: | 661 |
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| Sequence: | MGKSEKRVATHGVRCFAKIKMFLLALTCAYVSKSLSGTYMNSMLTQIERQFGIPTSIVGL
INGSFEIGNLLLIIFVSYFGTKLHRPIMIGVGCAVMGLGCFLISLPHFLMGQYEYETILP
TSNVSSNSFFCVENRSQTLNPTQDPSECVKEMKSLMWIYVLVGNIIRGIGETPIMPLGIS
YIEDFAKSENSPLYIGILETGMTIGPLIGLLLASSCANIYVDIESVNTDDLTITPTDTRW
VGAWWIGFLVCAGVNILTSFPFFFFPKTLPKEGLQENVDGTENAKEKKHRKKAKEEKRGI
TKDFFVFMKSLSCNPIYMLFILISVLQFNAFINSFTFMPKYLEQQYGKSTAEVVFLMGLY
MLPPICLGYLIGGLIMKKFKVTVKKAAHLAFWLCLSEYLLSFLSYVMTCDNFPVAGLTTS
YEGVQHQLYVENKVLADCNTRCNCSTNTWDPVCGDNGLAYMSACLAGCEKSVGTGTNMVF
QNCSCIQSSGNSSAVLGLCNKGPDCANKLQYFLIIAIFGCFIYSLAGIPGYMVLLRCIKS
EEKSLGVGLHAFCIRILAGIPAPIYFGALIDRTCLHWGTLKCGEPGACRMYDINSFRRLY
LGLPAALRGASFVPAFFILRLTRTFQFPGDIESSKTDHAEMKLTLKESECTEVLRSKVTE
D
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| BDBM50370232 |
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| n/a |
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| Name | BDBM50370232 |
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| Synonyms: | BA-41166E | L-5103 | RIFAMPIN | Rifadin | Rifampicin |
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| Type | Small organic molecule |
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| Emp. Form. | C43H58N4O12 |
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| Mol. Mass. | 822.9402 |
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| SMILES | CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C2=O)c2c(O)c(\C=N\N4CCN(C)CC4)c(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(O)c2c(O)c3C |r,c:33,t:3,35| |
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| Structure | 
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