| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Solute carrier family 22 member 6 |
|---|
| Ligand | BDBM50420190 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_837480 (CHEMBL2075968) |
|---|
| Ki | 2000000±n/a nM |
|---|
| Citation |  Koh, AS; Simmons-Willis, TA; Pritchard, JB; Grassl, SM; Ballatori, N Identification of a mechanism by which the methylmercury antidotes N-acetylcysteine and dimercaptopropanesulfonate enhance urinary metal excretion: transport by the renal organic anion transporter-1. Mol Pharmacol62:921-6 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Solute carrier family 22 member 6 |
|---|
| Name: | Solute carrier family 22 member 6 |
|---|
| Synonyms: | Oat1 | Organic anion transporter 1 | S22A6_RAT | Slc22a6 | rOAT1 | rROAT1 | renal organic anion transporter 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60784.17 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_838479 |
|---|
| Residue: | 551 |
|---|
| Sequence: | MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPPHHCRPPANANLSKD
GGLEAWLPLDKQGQPESCLRFTSPQWGPPFYNGTEANGTRVTEPCIDGWVYDNSTFPSTI
VTEWNLVCSHRAFRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA
YAPNYTVYCVFRLLSGMSLASIAINCMTLNVEWMPIHTRAYVGTLIGYVYSLGQFLLAGI
AYAVPHWRHLQLVVSVPFFIAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEE
GAKLSIEVLRTSLQKELTLSKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDL
QGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQMASLLLAGICILVNGIIPKSHT
IIRTSLAVLGKGCLASSFNCIFLYTGELYPTVIRQTGLGMGSTMARVGSIVSPLVSMTAE
FYPSMPLFIFGAVPVVASAVTALLPETLGQPLPDTVQDLKSRSRGKQNQQQQEQQKQMMP
LQASTQEKNGL
|
|
|
|---|
| BDBM50420190 |
|---|
| n/a |
|---|
| Name | BDBM50420190 |
|---|
| Synonyms: | 5052 | ACETYLCYSTEINE |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C5H9NO3S |
|---|
| Mol. Mass. | 163.195 |
|---|
| SMILES | CC(=O)N[C@@H](CS)C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
