| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Solute carrier family 22 member 1 |
|---|
| Ligand | BDBM50367247 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_838296 (CHEMBL2076244) |
|---|
| Ki | 930±n/a nM |
|---|
| Citation |  Gründemann, D; Gorboulev, V; Gambaryan, S; Veyhl, M; Koepsell, H Drug excretion mediated by a new prototype of polyspecific transporter. Nature372:549-552 (1994) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Solute carrier family 22 member 1 |
|---|
| Name: | Solute carrier family 22 member 1 |
|---|
| Synonyms: | Adrenaline alpha1 | Oct1 | Organic cation transporter 1 | S22A1_RAT | Slc22a1 | Solute carrier family 22 member 1 | adrenergic Alpha1 | rOCT1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 61538.40 |
|---|
| Organism: | RAT |
|---|
| Description: | Adrenaline alpha1 0 RAT::Q63089 |
|---|
| Residue: | 556 |
|---|
| Sequence: | MPTVDDVLEQVGEFGWFQKQAFLLLCLISASLAPIYVGIVFLGFTPGHYCQNPGVAELSQ
RCGWSQAEELNYTVPGLGPSDEASFLSQCMRYEVDWNQSTLDCVDPLSSLVANRSQLPLG
PCEHGWVYDTPGSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLCL
LVTTLVTSVSGVLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAIL
YQMAFTVGLVGLAGVAYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTRAV
RIMEQIAQKNGKVPPADLKMLCLEEDASEKRSPSFADLFRTPNLRKHTVILMYLWFSCAV
LYQGLIMHVGATGANLYLDFFYSSLVEFPAAFIILVTIDRIGRIYPIAASNLVTGAACLL
MIFIPHELHWLNVTLACLGRMGATIVLQMVCLVNAELYPTFIRNLGMMVCSALCDLGGIF
TPFMVFRLMEVWQALPLILFGVLGLTAGAMTLLLPETKGVALPETIEEAENLGRRKSKAK
ENTIYLQVQTGKSSST
|
|
|
|---|
| BDBM50367247 |
|---|
| n/a |
|---|
| Name | BDBM50367247 |
|---|
| Synonyms: | QUININE | Quinamm | Quinsan | cid_3034034 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H24N2O2 |
|---|
| Mol. Mass. | 324.4168 |
|---|
| SMILES | COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1 |THB:20:19:12.13:16.15,10:12:19.18:16.15| |
|---|
| Structure | 
|
|---|
Search and Browse
