| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 1 |
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| Ligand | BDBM50240908 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_837503 (CHEMBL2075991) |
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| IC50 | 10000±n/a nM |
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| Citation |  Dresser, MJ; Xiao, G; Leabman, MK; Gray, AT; Giacomini, KM Interactions of n-tetraalkylammonium compounds and biguanides with a human renal organic cation transporter (hOCT2). Pharm Res19:1244-7 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 1 |
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| Name: | Solute carrier family 22 member 1 |
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| Synonyms: | Adrenergic Alpha | OCT1 | Organic cation transporter 1 | S22A1_HUMAN | SLC22A1 | Solute carrier family 22 member 1 | hOCT1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 61154.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Adrenergic Alpha 0 HUMAN::O15245 |
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| Residue: | 554 |
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| Sequence: | MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKEN
TIYLKVQTSEPSGT
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| BDBM50240908 |
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| n/a |
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| Name | BDBM50240908 |
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| Synonyms: | CHEMBL170988 | N''-[(E)-amino(imino)methyl]-N-(2-phenylethyl)guanidine | N''-{amino[(2-phenylethyl)imino]methyl}guanidine | N-(2-phenylethyl)imidodicarbonimidic diamide | N-(2-phenylethyl)imidodicarbonimidic diamide(Phenformin) | N-amino(imino)methyl-N-phenethyliminomethanediamine(Phenformin) | PHENFORMIN |
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| Type | Small organic molecule |
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| Emp. Form. | C10H15N5 |
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| Mol. Mass. | 205.2596 |
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| SMILES | NC(=N)N=C(N)NCCc1ccccc1 |w:3.2| |
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| Structure | 
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