| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 6 |
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| Ligand | BDBM50328021 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_839175 (CHEMBL2077846) |
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| IC50 | 27000±n/a nM |
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| Citation |  Motojima, M; Hosokawa, A; Yamato, H; Muraki, T; Yoshioka, T Uraemic toxins induce proximal tubular injury via organic anion transporter 1-mediated uptake. Br J Pharmacol135:555-63 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 6 |
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| Name: | Solute carrier family 22 member 6 |
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| Synonyms: | OAT1 | Organic anion transporter 1 | PAH transporter | PAHT | Renal organic anion transporter 1 | S22A6_HUMAN | SLC22A6 | hOAT1 | hPAHT | hROAT1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 61831.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1487359 |
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| Residue: | 563 |
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| Sequence: | MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKN
GGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTI
VTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA
FAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGV
AYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREE
GAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDL
QGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQS
IVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAE
LYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRWAPTQKEAGIYPRKGKQT
RQQQEHQKYMVPLQASAQEKNGL
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| BDBM50328021 |
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| n/a |
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| Name | BDBM50328021 |
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| Synonyms: | (2-Hydroxy-benzoylamino)-acetic acid | 2-(2-hydroxybenzamido)acetic acid | 2-Hydroxyhippuric acid | CHEMBL586 | NSC-87566 | Salicyluric Acid (50-80-%) |
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| Type | Small organic molecule |
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| Emp. Form. | C9H9NO4 |
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| Mol. Mass. | 195.1721 |
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| SMILES | OC(=O)CNC(=O)c1ccccc1O |
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| Structure | 
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