| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 1 |
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| Ligand | BDBM50420217 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_838298 (CHEMBL2076246) |
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| IC50 | 37000±n/a nM |
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| Citation |  Arndt, P; Volk, C; Gorboulev, V; Budiman, T; Popp, C; Ulzheimer-Teuber, I; Akhoundova, A; Koppatz, S; Bamberg, E; Nagel, G; Koepsell, H Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1. Am J Physiol Renal Physiol281:454-68 (2001) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 1 |
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| Name: | Solute carrier family 22 member 1 |
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| Synonyms: | Adrenaline alpha1 | Oct1 | Organic cation transporter 1 | S22A1_RAT | Slc22a1 | Solute carrier family 22 member 1 | adrenergic Alpha1 | rOCT1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 61538.40 |
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| Organism: | RAT |
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| Description: | Adrenaline alpha1 0 RAT::Q63089 |
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| Residue: | 556 |
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| Sequence: | MPTVDDVLEQVGEFGWFQKQAFLLLCLISASLAPIYVGIVFLGFTPGHYCQNPGVAELSQ
RCGWSQAEELNYTVPGLGPSDEASFLSQCMRYEVDWNQSTLDCVDPLSSLVANRSQLPLG
PCEHGWVYDTPGSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLCL
LVTTLVTSVSGVLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAIL
YQMAFTVGLVGLAGVAYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTRAV
RIMEQIAQKNGKVPPADLKMLCLEEDASEKRSPSFADLFRTPNLRKHTVILMYLWFSCAV
LYQGLIMHVGATGANLYLDFFYSSLVEFPAAFIILVTIDRIGRIYPIAASNLVTGAACLL
MIFIPHELHWLNVTLACLGRMGATIVLQMVCLVNAELYPTFIRNLGMMVCSALCDLGGIF
TPFMVFRLMEVWQALPLILFGVLGLTAGAMTLLLPETKGVALPETIEEAENLGRRKSKAK
ENTIYLQVQTGKSSST
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| BDBM50420217 |
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| n/a |
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| Name | BDBM50420217 |
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| Synonyms: | METIPRENALINE |
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| Type | Small organic molecule |
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| Emp. Form. | C12H19NO3 |
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| Mol. Mass. | 225.2842 |
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| SMILES | COc1cc(ccc1O)C(O)CNC(C)C |
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| Structure | 
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