| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 2 |
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| Ligand | BDBM50206509 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_838297 (CHEMBL2076245) |
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| IC50 | 1700000±n/a nM |
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| Citation |  Arndt, P; Volk, C; Gorboulev, V; Budiman, T; Popp, C; Ulzheimer-Teuber, I; Akhoundova, A; Koppatz, S; Bamberg, E; Nagel, G; Koepsell, H Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1. Am J Physiol Renal Physiol281:454-68 (2001) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 2 |
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| Name: | Solute carrier family 22 member 2 |
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| Synonyms: | Adrenaline alpha2 | Oct2 | Organic cation transporter 2 | S22A2_RAT | Slc22a2 | Solute carrier family 22 member 2 | rOCT2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 62348.38 |
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| Organism: | RAT |
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| Description: | Adrenaline alpha2 0 RAT::Q9R0W2 |
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| Residue: | 555 |
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| Sequence: | MSTVDDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPDHHCWSPGAAKLSQ
RCGWSQAEELNYTVPGLGPSDEASFLSQCMRYEVDWNQSTLDCVDPLSSLAADRNQLPLG
PCEHGWVYNTPGSSIVTEFNLVCAHSWMLDLFQSVVNVGFFIGAMMIGYLADRFGRKFCL
LVTILINAISGALMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRMVGIC
YQIAFTVGLLILAGVAYVIPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKIVKAM
KIIKHIAKKNGKSVPVSLQNLTPDEDAGKKLNPSFLDLVRTPQIRKHTLILMYNWFTSSV
LYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRVGRRYPWAVSNMVAGAACLA
SVFIPDDLQWLKITIACLGRMGITMAYEMVCLVNAELYPTYIRNLGVLVCSSMCDIGGII
TPFLVYRLTDIWMEFPLVVFAVVGLVAGALVLLLPETKGKALPETIEDAENMQRPRKKKE
KRIYLQVKQADRPLS
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| BDBM50206509 |
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| n/a |
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| Name | BDBM50206509 |
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| Synonyms: | 4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfamoyl-benzoic acid anion | 4-Dipropylsulfamoyl-benzoic acid(probenecid) | Benemid | CHEMBL897 | PROBENECID | Probalan |
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| Type | Small organic molecule |
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| Emp. Form. | C13H19NO4S |
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| Mol. Mass. | 285.359 |
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| SMILES | CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O |
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| Structure | 
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