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TargetSnake venom metalloproteinase Bap1
LigandBDBM50420346
Substrate/Competitorn/a
Meas. Tech.ChEMBL_840308
IC50 34200±n/a nM
Citation Villalta-Romero FGortat AHerrera AEArguedas RQuesada Jde Melo RLCalvete JJMontero MMurillo RRucavado AGutiérrez JMPérez-Payá E Identification of new snake venom metalloproteinase inhibitors using compound screening and rational Peptide design. ACS Med Chem Lett 3:540-543 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Snake venom metalloproteinase Bap1
Name:Snake venom metalloproteinase Bap1
Synonyms:Bap-1 | Hemorrhagic metalloproteinase BaP1 | SVMP
Type:PROTEIN
Mol. Mass.:45929.07
Organism:Bothrops asper
Description:ChEMBL_840308
Residue:408
Sequence:
MIEVLLVTICLAVFPYQGSSIILESGNVNDYEVVYPRKVTELPKGAVQPKYEDAMQYEFK
VNGEPVVLHLEKNKGLFSEDYSETHYSPDGRKIITYPSFEDHCYYHGRIENDADSTASIS
ACNGLKGHFKLQGETYLIEPLKLSDSEAHAVYKYENVEKEDEAPKMCGVTETNWESYEPI
KKASQSNLTPEQQRFSPRYIELAVVADHGIFTKYNSNLNTIRTRVHEMLNTVNGFYRSVD
VHAPLANLEVWSKQDLIKVQKDSSKTLKSFGEWRERDLLPRISHDHAQLLTAVVFDGNTI
GRAYTGGMCDPRHSVGVVRDHSKNNLWVAVTMAHELGHNLGIHHDTGSCSCGAKSCIMAS
VLSKVLSYEFSDCSQNQYETYLTNHNPQCILNKPLLTVSGNELLEAGE
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  Blast E-value cutoff:
BDBM50420346
n/a
NameBDBM50420346
Synonyms:CHEMBL2089166
TypeSmall organic molecule
Emp. Form.C26H33N5O4
Mol. Mass.479.5713
SMILESCC(C)C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)NO |r|
Structure
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