| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM82493 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_38152 (CHEMBL651043) |
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| Ki | 58±n/a nM |
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| Citation |  Markovich, KM; Tantishaiyakul, V; Hamada, A; Miller, DD; Romstedt, KJ; Shams, G; Shin, Y; Fraundorfer, PF; Doyle, K; Feller, DR Synthesis of halogenated trimetoquinol derivatives and evaluation of their beta-agonist and thromboxane A2 (TXA2) antagonist activities. J Med Chem35:466-79 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2_CAVPO | Adrb2 | adrenergic Beta2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46993.24 |
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| Organism: | GUINEA PIG |
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| Description: | adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4 |
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| Residue: | 418 |
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| Sequence: | MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKD
AINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRF
HTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNG
KTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
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| BDBM82493 |
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| n/a |
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| Name | BDBM82493 |
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| Synonyms: | CAS_128658 | NSC_128658 | TMQ, (+/-)-8-Fluoro |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22FNO5 |
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| Mol. Mass. | 363.3801 |
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| SMILES | COc1cc(CC2NCCc3cc(O)c(O)c(F)c23)cc(OC)c1OC |
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| Structure | 
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