| Reaction Details |
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 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
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| Ligand | BDBM82498 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_209427 |
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| IC50 | 158000±n/a nM |
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| Citation |  Markovich, KM; Tantishaiyakul, V; Hamada, A; Miller, DD; Romstedt, KJ; Shams, G; Shin, Y; Fraundorfer, PF; Doyle, K; Feller, DR Synthesis of halogenated trimetoquinol derivatives and evaluation of their beta-agonist and thromboxane A2 (TXA2) antagonist activities. J Med Chem35:466-79 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Thromboxane A2 receptor |
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| Name: | Thromboxane A2 receptor |
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| Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
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| Type: | Enyzme |
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| Mol. Mass.: | 37445.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21731 |
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| Residue: | 343 |
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| Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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| BDBM82498 |
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| n/a |
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| Name | BDBM82498 |
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| Synonyms: | TMQ, 5,8-Difluoro |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21F2NO5 |
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| Mol. Mass. | 381.3705 |
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| SMILES | COc1cc(CC2NCCc3c(F)c(O)c(O)c(F)c23)cc(OC)c1OC |
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| Structure | 
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