Reaction Details |
| Report a problem with these data |
Target | Gag-Pol polyprotein [489-587] |
---|
Ligand | BDBM50455442 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_158029 (CHEMBL877854) |
---|
IC50 | 162±n/a nM |
---|
Citation | Pérez, C; Pastor, M; Ortiz, AR; Gago, F Comparative binding energy analysis of HIV-1 protease inhibitors: incorporation of solvent effects and validation as a powerful tool in receptor-based drug design. J Med Chem41:836-52 (1998) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Gag-Pol polyprotein [489-587] |
---|
Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
BDBM50455442 |
---|
n/a |
---|
Name | BDBM50455442 |
Synonyms: | CHEMBL2367848 |
Type | Small organic molecule |
Emp. Form. | C29H40N2O6 |
Mol. Mass. | 512.6377 |
SMILES | [H][C@](O)(C[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(C(C)C)C(O)=O)[C@]([H])(Cc1ccccc1)NC(=O)OC(C)(C)C |
Structure |
|