| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 1 |
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| Ligand | BDBM50423467 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_461985 (CHEMBL944828) |
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| Kd | 0.603000±n/a nM |
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| Citation |  Troxler, T; Enz, A; Hoyer, D; Langenegger, D; Neumann, P; Pfäffli, P; Schoeffter, P; Hurth, K Ergoline derivatives as highly potent and selective antagonists at the somatostatin sst 1 receptor. Bioorg Med Chem Lett18:979-82 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 1 |
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| Name: | Somatostatin receptor type 1 |
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| Synonyms: | SOMATOSTATIN SST1 | SRIF-2 | SS1R | SSR1_RAT | Somatostatin receptor | Somatostatin receptor type 1 | Sstr1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42752.93 |
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| Organism: | RAT |
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| Description: | SOMATOSTATIN SST1 SSTR1 RAT::P28646 |
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| Residue: | 391 |
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| Sequence: | MFPNGTAPSPTSSPSSSPGGCGEGVCSRGPGSGAADGMEEPGRNSSQNGTLSEGQGSAIL
ISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLL
RHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG
VWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAIC
LCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQD
DATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKS
RAYSVEDFQPENLESGGVFRNGTCASRISTL
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| BDBM50423467 |
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| n/a |
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| Name | BDBM50423467 |
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| Synonyms: | CHEMBL252428 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H27ClF2N4O |
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| Mol. Mass. | 484.969 |
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| SMILES | CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Cl)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc(F)c(F)c1 |
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| Structure | 
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