| Reaction Details |
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 | Report a problem with these data |
| Target | Sex hormone-binding globulin |
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| Ligand | BDBM17289 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_466706 (CHEMBL922711) |
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| Kd | 6.6±n/a nM |
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| Citation |  Cherkasov, A; Ban, F; Santos-Filho, O; Thorsteinson, N; Fallahi, M; Hammond, GL An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin. J Med Chem51:2047-56 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sex hormone-binding globulin |
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| Name: | Sex hormone-binding globulin |
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| Synonyms: | SHBG | SHBG_HUMAN | Testis-specific androgen-binding protein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43780.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_466706 |
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| Residue: | 402 |
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| Sequence: | MESRGPLATSRLLLLLLLLLLRHTRQGWALRPVLPTQSAHDPPAVHLSNGPGQEPIAVMT
FDLTKITKTSSSFEVRTWDPEGVIFYGDTNPKDDWFMLGLRDGRPEIQLHNHWAQLTVGA
GPRLDDGRWHQVEVKMEGDSVLLEVDGEEVLRLRQVSGPLTSKRHPIMRIALGGLLFPAS
NLRLPLVPALDGCLRRDSWLDKQAEISASAPTSLRSCDVESNPGIFLPPGTQAEFNLRDI
PQPHAEPWAFSLDLGLKQAAGSGHLLALGTPENPSWLSLHLQDQKVVLSSGSGPGLDLPL
VLGLPLQLKLSMSRVVLSQGSKMKALALPPLGLAPLLNLWAKPQGRLFLGALPGEDSSTS
FCLNGLWAQGQRLDVDQALNRSHEIWTHSCPQSPGNGTDASH
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| BDBM17289 |
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| n/a |
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| Name | BDBM17289 |
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| Synonyms: | (1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-trien-14-one | CHEMBL1405 | Estrone | Estrone (E1) | Estrone, 15 | Estrovarin | Kestrone | Theelin | Unigen | [2,4,6,7-3H]-E1 | [2,4,6,7-3H]-Estrone | folliculin |
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| Type | Steroid |
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| Emp. Form. | C18H22O2 |
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| Mol. Mass. | 270.3661 |
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| SMILES | [H][C@@]12CCC(=O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H] |
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| Structure | 
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