| Reaction Details |
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 | Report a problem with these data |
| Target | Sex hormone-binding globulin |
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| Ligand | BDBM50240921 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_466706 (CHEMBL922711) |
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| Kd | 309±n/a nM |
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| Citation |  Cherkasov, A; Ban, F; Santos-Filho, O; Thorsteinson, N; Fallahi, M; Hammond, GL An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin. J Med Chem51:2047-56 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sex hormone-binding globulin |
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| Name: | Sex hormone-binding globulin |
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| Synonyms: | SHBG | SHBG_HUMAN | Testis-specific androgen-binding protein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43780.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_466706 |
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| Residue: | 402 |
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| Sequence: | MESRGPLATSRLLLLLLLLLLRHTRQGWALRPVLPTQSAHDPPAVHLSNGPGQEPIAVMT
FDLTKITKTSSSFEVRTWDPEGVIFYGDTNPKDDWFMLGLRDGRPEIQLHNHWAQLTVGA
GPRLDDGRWHQVEVKMEGDSVLLEVDGEEVLRLRQVSGPLTSKRHPIMRIALGGLLFPAS
NLRLPLVPALDGCLRRDSWLDKQAEISASAPTSLRSCDVESNPGIFLPPGTQAEFNLRDI
PQPHAEPWAFSLDLGLKQAAGSGHLLALGTPENPSWLSLHLQDQKVVLSSGSGPGLDLPL
VLGLPLQLKLSMSRVVLSQGSKMKALALPPLGLAPLLNLWAKPQGRLFLGALPGEDSSTS
FCLNGLWAQGQRLDVDQALNRSHEIWTHSCPQSPGNGTDASH
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| BDBM50240921 |
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| n/a |
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| Name | BDBM50240921 |
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| Synonyms: | (-)-matairesinol | (2R,3R)-2,3-Bis(4-hydroxy-3-methoxybenzyl)-4-butanolide | (3R,4R)-3,4-Bis-(4-hydroxy-3-methoxy-benzyl)-dihydro-furan-2-one | (3R,4R)-3,4-bis(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one | CHEMBL425148 | MATAIRESINOL |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22O6 |
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| Mol. Mass. | 358.3851 |
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| SMILES | COc1cc(C[C@H]2COC(=O)[C@@H]2Cc2ccc(O)c(OC)c2)ccc1O |r| |
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| Structure | 
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