| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
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| Ligand | BDBM50423972 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_935595 (CHEMBL2320377) |
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| EC50 | >10000±n/a nM |
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| Citation |  Futatsugi, K; Mascitti, V; Guimarães, CR; Morishita, N; Cai, C; DeNinno, MP; Gao, H; Hamilton, MD; Hank, R; Harris, AR; Kung, DW; Lavergne, SY; Lefker, BA; Lopaze, MG; McClure, KF; Munchhof, MJ; Preville, C; Robinson, RP; Wright, SW; Bonin, PD; Cornelius, P; Chen, Y; Kalgutkar, AS From partial to full agonism: identification of a novel 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole as a full agonist of the human GPR119 receptor. Bioorg Med Chem Lett23:194-7 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-dependent insulinotropic receptor |
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| Name: | Glucose-dependent insulinotropic receptor |
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| Synonyms: | G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor |
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| Type: | Protein |
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| Mol. Mass.: | 36901.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TDV5 |
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| Residue: | 335 |
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| Sequence: | MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
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| BDBM50423972 |
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| n/a |
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| Name | BDBM50423972 |
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| Synonyms: | CHEMBL2313406 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H29N5O4S |
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| Mol. Mass. | 435.54 |
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| SMILES | CC(C)OC(=O)N1CCC(CC1)n1cc(CNc2ccc(nc2C)S(C)(=O)=O)cn1 |
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| Structure | 
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