| Reaction Details |
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 | Report a problem with these data |
| Target | NAD-dependent protein deacetylase |
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| Ligand | BDBM50156760 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_936768 (CHEMBL2320160) |
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| IC50 | 193800±n/a nM |
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| Citation |  Zheng, W Sirtuins as emerging anti-parasitic targets. Eur J Med Chem59:132-40 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| NAD-dependent protein deacetylase |
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| Name: | NAD-dependent protein deacetylase |
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| Synonyms: | Putative silent information regulator 2 | SIR2-like protein | SIR2RP1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40532.98 |
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| Organism: | Leishmania infantum |
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| Description: | ChEMBL_936768 |
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| Residue: | 373 |
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| Sequence: | MTASPRAPHQEHVLGEPTLEGLAHYIREKNVRRILVLVGAGASVAAGIPDFRSPDTGIYA
NLGKYNLEDPTDAFSLTLLREKPEIFYSIARELNLWPGHFQPTAVHHFIRLLQDEGRLLR
CCTQNIDGLEKAAGVSPELLVEAHGSFAAAACIECHTPFSIEQNYLEAMSGTVSRCSTCG
GIVKPNVVFFGENLPDAFFDALHHDAPIAELVIIIGTSMQVHPFALLPCVVPKSVPRVVM
NRERVGGLLFRFPDDPLNTVHEDAVAKEGRSSSSQSRSPSASPRREEGGTEDSPSSPNEE
VEEASTSSSSDGYGQYGDYHAHPDVCRDVLFRGDCQENVVTLAEYLGLSEALAKRMRLSD
AAPATAQRAPNET
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| BDBM50156760 |
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| n/a |
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| Name | BDBM50156760 |
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| Synonyms: | (E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide | 2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide | 2-{[(1-(2-hydroxy-naphthalen-1-yl)meth-(E)-ylidene]amino}-N-(1-phenylethyl)-benzamide | 2-{[1-(2-hydroxynaphthalen-1-yl)meth-(E)-ylene]amino}-N-(1-phenylethyl)benzamide | CHEMBL380797 | Sirtinol |
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| Type | Small organic molecule |
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| Emp. Form. | C26H22N2O2 |
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| Mol. Mass. | 394.4651 |
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| SMILES | CC(NC(=O)c1ccccc1\N=C\c1c(O)ccc2ccccc12)c1ccccc1 |
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| Structure | 
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