| Reaction Details |
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 | Report a problem with these data |
| Target | Acrosin |
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| Ligand | BDBM50424443 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_936791 (CHEMBL2320183) |
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| IC50 | 80000±n/a nM |
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| Citation |  Chen, Q; Tian, W; Han, G; Qi, J; Zheng, C; Zhou, Y; Ding, L; Zhao, J; Zhu, J; Lv, J; Sheng, C Design and synthesis of novel benzoheterocyclic derivatives as human acrosin inhibitors by scaffold hopping. Eur J Med Chem59:176-82 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acrosin |
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| Name: | Acrosin |
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| Synonyms: | ACR | ACRO_HUMAN | ACRS |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45865.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1365286 |
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| Residue: | 421 |
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| Sequence: | MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSL
QIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPL
QERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVA
GWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDS
GGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSA
TPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPASP
LPPPPPPPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGKNHYDMETTELPELTST
S
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| BDBM50424443 |
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| n/a |
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| Name | BDBM50424443 |
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| Synonyms: | CHEMBL2316070 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18FN5O4S |
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| Mol. Mass. | 407.419 |
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| SMILES | OCCNC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccccc1F |
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| Structure | 
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