| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50424511 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_937678 (CHEMBL2317192) |
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| Ki | 68±n/a nM |
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| Citation |  Yaziji, V; Rodríguez, D; Coelho, A; García-Mera, X; El Maatougui, A; Brea, J; Loza, MI; Cadavid, MI; Gutiérrez-de-Terán, H; Sotelo, E Selective and potent adenosine A3 receptor antagonists by methoxyaryl substitution on the N-(2,6-diarylpyrimidin-4-yl)acetamide scaffold. Eur J Med Chem59:235-42 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50424511 |
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| n/a |
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| Name | BDBM50424511 |
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| Synonyms: | CHEMBL2311741 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H19N3O3 |
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| Mol. Mass. | 349.3832 |
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| SMILES | COc1cccc(c1)-c1cc(NC(C)=O)nc(n1)-c1cccc(OC)c1 |
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| Structure | 
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