| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 11 |
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| Ligand | BDBM50424996 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_936026 (CHEMBL2318992) |
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| IC50 | 852±n/a nM |
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| Citation |  Marek, L; Hamacher, A; Hansen, FK; Kuna, K; Gohlke, H; Kassack, MU; Kurz, T Histone deacetylase (HDAC) inhibitors with a novel connecting unit linker region reveal a selectivity profile for HDAC4 and HDAC5 with improved activity against chemoresistant cancer cells. J Med Chem56:427-36 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 11 |
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| Name: | Histone deacetylase 11 |
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| Synonyms: | HD11 | HDA11_HUMAN | HDAC11 | Human HDAC11 |
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| Type: | Chromatin regulator; hydrolase; repressor |
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| Mol. Mass.: | 39187.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q96DB2 |
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| Residue: | 347 |
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| Sequence: | MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
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| BDBM50424996 |
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| n/a |
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| Name | BDBM50424996 |
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| Synonyms: | CHEMBL2312168 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H22N2O4 |
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| Mol. Mass. | 294.3462 |
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| SMILES | Cc1cc(C)cc(c1)C(=O)NOCCCCCC(=O)NO |
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| Structure | 
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