| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mu-type opioid receptor |
|---|
| Ligand | BDBM50425524 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_936065 (CHEMBL2319307) |
|---|
| Ki | 37±n/a nM |
|---|
| Citation |  Bornot, A; Bauer, U; Brown, A; Firth, M; Hellawell, C; Engkvist, O Systematic exploration of dual-acting modulators from a combined medicinal chemistry and biology perspective. J Med Chem56:1197-210 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mu-type opioid receptor |
|---|
| Name: | Mu-type opioid receptor |
|---|
| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 44789.51 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35372 |
|---|
| Residue: | 400 |
|---|
| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
|
|
|
|---|
| BDBM50425524 |
|---|
| n/a |
|---|
| Name | BDBM50425524 |
|---|
| Synonyms: | CHEMBL2313628 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H31ClN4O2 |
|---|
| Mol. Mass. | 467.003 |
|---|
| SMILES | CCC(=O)N(C1CCN(CCn2c3ccccc3n(C(C)=C)c2=O)CC1)c1cccc(Cl)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
