| Reaction Details |
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 | Report a problem with these data |
| Target | Thioredoxin |
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| Ligand | BDBM50426063 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_934906 (CHEMBL2319792) |
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| IC50 | 450±n/a nM |
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| Citation |  DiRaimondo, TR; Plugis, NM; Jin, X; Khosla, C Selective inhibition of extracellular thioredoxin by asymmetric disulfides. J Med Chem56:1301-10 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thioredoxin |
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| Name: | Thioredoxin |
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| Synonyms: | ADF | ATL-derived factor | SASP | Surface-associated sulphydryl protein | THIO_HUMAN | TRDX | TRX | TRX1 | TXN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 11732.84 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_934906 |
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| Residue: | 105 |
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| Sequence: | MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVD
DCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELV
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| BDBM50426063 |
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| n/a |
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| Name | BDBM50426063 |
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| Synonyms: | CHEMBL2315290 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H18N2S2 |
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| Mol. Mass. | 290.447 |
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| SMILES | C1CCC(CC1)SSc1nc(c[nH]1)-c1ccccc1 |
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| Structure | 
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