Reaction Details |
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Target | Galanin receptor type 1 |
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Ligand | BDBM50426597 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_938964 (CHEMBL2328546) |
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Ki | 3.8±n/a nM |
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Citation | Green, BR; Klein, BD; Lee, HK; Smith, MD; Steve White, H; Bulaj, G Cyclic analogs of galanin and neuropeptide Y by hydrocarbon stapling. Bioorg Med Chem21:303-10 (2012) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Galanin receptor type 1 |
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Name: | Galanin receptor type 1 |
Synonyms: | GAL1-R | GALNR | GALNR1 | GALR1 | GALR1_HUMAN | Galanin R1 | Galanin receptor 1 | Galanin receptor type 1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 38976.60 |
Organism: | Homo sapiens (Human) |
Description: | Galanin R1 GALR1 HUMAN::P47211 |
Residue: | 349 |
Sequence: | MELAVGNLSEGNASWPEPPAPEPGPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLAR
SKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSML
VSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASPVAYHQGLFHPR
ASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEA
SKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNP
IIYAFLSENFRKAYKQVFKCHIRKDSHLSDTKESKSRIDTPPSTNCTHV
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BDBM50426597 |
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n/a |
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Name | BDBM50426597 |
Synonyms: | CHEMBL2324950 |
Type | Small organic molecule |
Emp. Form. | C102H166N26O23 |
Mol. Mass. | 2124.5698 |
SMILES | CNCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@]1(C)CCC\C=C/CCC[C@](C)(NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](CCCCN)C(N)=O |r,c:106| |
Structure |
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